› 2q5r

X-ray diffraction
2.3Å resolution

Structure of apo Staphylococcus aureus D-tagatose-6-phosphate kinase

Released:
DOI: 10.2210/pdb2q5r/pdb
Model geometry
Fit model/data
PDB entry 2q5r coloured by chain, front view.
PDB entry 2q5r coloured by chain, side view.
PDB entry 2q5r coloured by chain, top view.
Source organism: Staphylococcus aureus
Entry authors: McGrath TE, Soloveychik M, Romanov V, Thambipillai D, Dharamsi A, Virag C, Domagala M, Pai EF, Edwards AM, Battaile K, Chirgadze NY

Function and Biology Details

Reaction catalysed: 
ATP + D-tagatose 6-phosphate = ADP + D-tagatose 1,6-bisphosphate
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177177 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tagatose-6-phosphate kinase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 330 amino acids
Theoretical weight: 36.2 KDa
Source organism: Staphylococcus aureus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5HE12 (Residues: 1-310; Coverage: 100%)
Gene names: SACOL2184, lacC
Sequence domains: pfkB family carbohydrate kinase
Structure domains: UDP-N-acetylmuramoyl-L-alanine:D-glutamate ligase

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: APS BEAMLINE 17-ID
Spacegroup: P21
Unit cell:
a: 76.952Å b: 96.94Å c: 94.485Å
α: 90° β: 94.42° γ: 90°
R-values:
R R work R free
0.218 0.215 0.283
Expression system: Escherichia coli BL21(DE3)

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