› 2qc5

X-ray diffraction
1.8Å resolution

Streptogramin B lyase structure

Released:
DOI: 10.2210/pdb2qc5/pdb
PDB entry 2qc5 coloured by chain, front view.
PDB entry 2qc5 coloured by chain, side view.
PDB entry 2qc5 coloured by chain, top view.
Source organism: Staphylococcus cohnii
Primary publication:
Crystal structure and mechanism of the Staphylococcus cohnii virginiamycin B lyase (Vgb).
Lipka M, Filipek R, Bochtler M
Biochemistry 47 4257-65 (2008)
PMID: 18341294

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-131493 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Virginiamycin B lyase Chain: A
Molecule details ›
Chain: A
Length: 300 amino acids
Theoretical weight: 32.97 KDa
Source organism: Staphylococcus cohnii
Expression system: Escherichia coli
UniProt:
  • Canonical: O87275 (Residues: 1-295; Coverage: 100%)
Gene name: vgbB
Structure domains: YVTN repeat-like/Quinoprotein amine dehydrogenase

Ligands and Environments

1 bound ligand:
Ligand IOD 2 x IOD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P212121
Unit cell:
a: 60.465Å b: 68.117Å c: 73.212Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.18 0.179 0.212
Expression system: Escherichia coli

Quick links

Citations

2 review citations

The genomic enzymology of antibiotic resistance.
Morar et al. (2010)
1 more

2 mentions without citation

Cholera- and anthrax-like toxins are among several new ADP-ribosyltransferases.
Fieldhouse et al. (2010)
1 more