2qcw

X-ray diffraction
2.49Å resolution

Crystal Structure of Bone Morphogenetic Protein-6 (BMP-6)

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-149503 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Bone morphogenetic protein 6 Chains: A, B
Molecule details ›
Chains: A, B
Length: 132 amino acids
Theoretical weight: 14.89 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P22004 (Residues: 382-513; Coverage: 27%)
Gene names: BMP6, VGR
Sequence domains: Transforming growth factor beta like domain
Structure domains: Cystine-knot cytokines

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P3121
Unit cell:
a: 97.446Å b: 97.446Å c: 87.377Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.235 0.233 0.276
Expression system: Escherichia coli BL21