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› 2qdq

X-ray diffraction
2.2Å resolution

Crystal structure of the talin dimerisation domain

Released:
DOI: 10.2210/pdb2qdq/pdb
Model geometry
Fit model/data
PDB entry 2qdq coloured by chain, front view.
PDB entry 2qdq coloured by chain, side view.
PDB entry 2qdq coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
The structure of the C-terminal actin-binding domain of talin.
Gingras AR, Bate N, Goult BT, Hazelwood L, Canestrelli I, Grossmann JG, Liu H, Putz NS, Roberts GC, Volkmann N, Hanein D, Barsukov IL, Critchley DR
OpenAccess logo EMBO J 27 458-69 (2008)
PMID: 18157087

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150646 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Talin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 50 amino acids
Theoretical weight: 5.85 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P26039 (Residues: 2494-2541; Coverage: 2%)
Gene names: Tln, Tln1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
X-ray source: ESRF BEAMLINE ID23-1, ESRF BEAMLINE ID14-3
Spacegroup: P4132
Unit cell:
a: 98.82Å b: 98.82Å c: 98.82Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.257 0.257 0.315
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

36 review citations

Environmental sensing through focal adhesions.
Geiger et al. (2009)
35 more

6 mentions without citation

The structure of the C-terminal actin-binding domain of talin.
Gingras et al. (2008)
5 more