› 2qef

X-ray diffraction
1.6Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-115798 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(*DCP*DGP*DCP*DGP*DAP*DAP*DTP*(ZDU)P*DCP*(7GU)P*DCP*DG)-3') Chains: A, B
Molecule details ›
Chains: A, B
Length: 12 nucleotides
Theoretical weight: 3.71 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
2 modified residues:
Ligand ZDU 2 x ZDU
Ligand 7GU 2 x 7GU

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P212121
Unit cell:
a: 24.858Å b: 41.057Å c: 66.615Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.181 0.231
Expression system: Not provided

Quick links

Citations

6 citation in other articles

Probing transient Hoogsteen hydrogen bonds in canonical duplex DNA using NMR relaxation dispersion and single-atom substitution.
Nikolova et al. (2012)
5 more

4 mentions without citation

Structure-based DNA-targeting strategies with small molecule ligands for drug discovery.
Sheng et al. (2013)
3 more