› 2qjx

X-ray diffraction
1.9Å resolution

Structural Basis of Microtubule Plus End Tracking by XMAP215, CLIP-170 and EB1

Released:
DOI: 10.2210/pdb2qjx/pdb
PDB entry 2qjx coloured by chain, front view.
PDB entry 2qjx coloured by chain, side view.
PDB entry 2qjx coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1.
Slep KC, Vale RD
Mol Cell 27 976-91 (2007)
PMID: 17889670

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153997 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein BIM1 Chain: A
Molecule details ›
Chain: A
Length: 127 amino acids
Theoretical weight: 15.16 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: P40013 (Residues: 1-124; Coverage: 36%)
Gene names: BIM1, YER016W
Structure domains: Calponin-like domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 3 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: P21212
Unit cell:
a: 35.849Å b: 102.502Å c: 31.334Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.193 0.193 0.225
Expression system: Escherichia coli

Quick links

Citations

35 review citations

Tracking the ends: a dynamic protein network controls the fate of microtubule tips.
Akhmanova et al. (2008)
34 more

3 mentions without citation

Mammalian end binding proteins control persistent microtubule growth.
Komarova et al. (2009)
2 more