2qk2

X-ray diffraction
2.1Å resolution

Structural Basis of Microtubule Plus End Tracking by XMAP215, CLIP-170 and EB1

Released:
Source organism: Drosophila melanogaster
Primary publication:
Structural basis of microtubule plus end tracking by XMAP215, CLIP-170, and EB1.
Mol Cell 27 976-91 (2007)
PMID: 17889670

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194237 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Protein mini spindles Chain: A
Molecule details ›
Chain: A
Length: 242 amino acids
Theoretical weight: 26.76 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9VEZ3 (Residues: 267-505; Coverage: 12%)
Gene names: CG5000, msps
Sequence domains: XMAP215/Dis1/CLASP, TOG domain
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: ALS BEAMLINE 8.3.1
Spacegroup: C2221
Unit cell:
a: 91.37Å b: 113.414Å c: 78.556Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.202 0.202 0.217
Expression system: Escherichia coli