› 2qlk

X-ray diffraction
2.02Å resolution

Adenovirus AD35 fibre head

Released:
DOI: 10.2210/pdb2qlk/pdb
PDB entry 2qlk coloured by chain, front view.
PDB entry 2qlk coloured by chain, side view.
PDB entry 2qlk coloured by chain, top view.
Source organism: Human adenovirus 35
Primary publication:
Identification of CD46 binding sites within the adenovirus serotype 35 fiber knob.
Wang H, Liaw YC, Stone D, Kalyuzhniy O, Amiraslanov I, Tuve S, Verlinde CL, Shayakhmetov D, Stehle T, Roffler S, Lieber A
J Virol 81 12785-92 (2007)
PMID: 17898059

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
homo trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-182011 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Adenoviral fibre protein knob domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 213 amino acids
Theoretical weight: 23.66 KDa
Source organism: Human adenovirus 35
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q7T925 (Residues: 123-323; Coverage: 62%)
Gene name: L5
Sequence domains: Adenoviral fibre protein (knob domain)
Structure domains: Adenovirus pIV-related, attachment domain

Ligands and Environments

1 bound ligand:
Ligand GOL 1 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSRRC BEAMLINE BL13B1
Spacegroup: R3
Unit cell:
a: 87.831Å b: 87.831Å c: 53.897Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.2 0.257
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

15 review citations

Adenoviruses: update on structure and function.
Russell WC. (2009)
14 more

4 mentions without citation

Designer Oncolytic Adenovirus: Coming of Age.
Baker et al. (2018)
3 more