› 2qnr

X-ray diffraction
2.6Å resolution

Human septin 2 in complex with GDP

Released:
DOI: 10.2210/pdb2qnr/pdb
PDB entry 2qnr coloured by chain, front view.
PDB entry 2qnr coloured by chain, side view.
PDB entry 2qnr coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Rabeh WM, Nedyalkova L, Tempel W, Landry R, Crombet L, Kozieradzki I, Senisterra G, Vedadi M, Arrowsmith CH, Edwards AM, Sundstrom M, Weigelt J, Bochkarev A, Park H, Structural Genomics Consortium (SGC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172159 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Septin-2 Chains: A, B
Molecule details ›
Chains: A, B
Length: 301 amino acids
Theoretical weight: 35.01 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q15019 (Residues: 22-320; Coverage: 83%)
Gene names: DIFF6, KIAA0158, NEDD5, SEPT2, SEPTIN2
Sequence domains: Septin
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

2 bound ligands:
Ligand GDP 2 x GDP
Ligand UNX 4 x UNX
1 modified residue:
Ligand MSE 10 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE A1
Spacegroup: C2
Unit cell:
a: 164.536Å b: 52.295Å c: 110.944Å
α: 90° β: 132.48° γ: 90°
R-values:
R R work R free
0.237 0.234 0.293
Expression system: Escherichia coli

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