› 2qp2

X-ray diffraction
2Å resolution

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181800 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
MACPF domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 511 amino acids
Theoretical weight: 57.16 KDa
Source organism: Photorhabdus laumondii subsp. laumondii
Expression system: Escherichia coli
UniProt:
  • Canonical: Q7N6X0 (Residues: 1-510; Coverage: 100%)
Gene name: plu1415
Sequence domains: MAC/Perforin domain
Structure domains: Vitelline Membrane Outer Layer Protein I, subunit A

Ligands and Environments

1 bound ligand:
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELLIOTT GX-18
Spacegroup: P21212
Unit cell:
a: 97.439Å b: 154.507Å c: 43.917Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.182 0.18 0.204
Expression system: Escherichia coli

Quick links

Citations

48 review citations

Low-grade inflammation as a key mediator of the pathogenesis of osteoarthritis.
Robinson et al. (2016)
47 more

20 mentions without citation

The MACPF/CDC family of pore-forming toxins.
Rosado et al. (2008)
19 more