› 2qsr

X-ray diffraction
3.1Å resolution

Crystal structure of C-terminal domain of transcription-repair coupling factor

Released:
DOI: 10.2210/pdb2qsr/pdb
PDB entry 2qsr coloured by chain, front view.
PDB entry 2qsr coloured by chain, side view.
PDB entry 2qsr coloured by chain, top view.
Source organism: Streptococcus pneumoniae R6
Entry authors: Ramagopal UA, Toro R, Gilmore M, Bain K, Iizuka M, Wasserman S, Rodgers L, Sauder JM, Burley SK, Almo SC, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-184174 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Transcription-repair-coupling factor Chain: A
Molecule details ›
Chain: A
Length: 173 amino acids
Theoretical weight: 20.51 KDa
Source organism: Streptococcus pneumoniae R6
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8DRQ1 (Residues: 1007-1168; Coverage: 14%)
Gene names: mfd, spr0006
Sequence domains: TRCF domain
Structure domains: Transcription-repair-coupling factor, D7 domain

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 2 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 31-ID
Spacegroup: P6122
Unit cell:
a: 84.891Å b: 84.891Å c: 122.021Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.187 0.184 0.243
Expression system: Escherichia coli BL21(DE3)

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