› 2qtn

X-ray diffraction
2.4Å resolution

Crystal Structure of Nicotinate Mononucleotide Adenylyltransferase

Released:
DOI: 10.2210/pdb2qtn/pdb
PDB entry 2qtn coloured by chain, front view.
PDB entry 2qtn coloured by chain, side view.
PDB entry 2qtn coloured by chain, top view.
Source organism: Bacillus anthracis
Primary publication:
Kinetic and X-ray structural evidence for negative cooperativity in substrate binding to nicotinate mononucleotide adenylyltransferase (NMAT) from Bacillus anthracis.
Sershon VC, Santarsiero BD, Mesecar AD
J Mol Biol 385 867-88 (2009)
PMID: 18977360

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-163200 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Nicotinate (Nicotinamide) nucleotide adenylyltransferase Chains: A, B
Molecule details ›
Chains: A, B
Length: 189 amino acids
Theoretical weight: 21.98 KDa
Source organism: Bacillus anthracis
Expression system: Escherichia coli
Structure domains: HUPs

Ligands and Environments

3 bound ligands:
Ligand MG 2 x MG
Ligand GOL 6 x GOL
Ligand NCN 1 x NCN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P61
Unit cell:
a: 95.895Å b: 95.895Å c: 84.532Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.204 0.204 0.287
Expression system: Escherichia coli

Quick links

Citations

1 review citation

Nicotinamide/nicotinic acid mononucleotide adenylyltransferase, new insights into an ancient enzyme.
Zhai et al. (2009)
7 other articles

3 mentions without citation

Structure of nicotinic acid mononucleotide adenylyltransferase from Bacillus anthracis.
Lu et al. (2008)
2 more