› 2qvg

X-ray diffraction
1.5Å resolution

The crystal structure of a two-component response regulator from Legionella pneumophila

Released:
DOI: 10.2210/pdb2qvg/pdb
PDB entry 2qvg coloured by chain, front view.
PDB entry 2qvg coloured by chain, side view.
PDB entry 2qvg coloured by chain, top view.
Source organism: Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Entry authors: Tyagi R, Eswaramoorthy S, Burley SK, Swaminathan S, New York SGX Research Center for Structural Genomics (NYSGXRC)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178601 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Response regulatory domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 143 amino acids
Theoretical weight: 16.69 KDa
Source organism: Legionella pneumophila subsp. pneumophila str. Philadelphia 1
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q5ZSR0 (Residues: 5-136; Coverage: 97%)
Gene name: lpg2457
Sequence domains: Response regulator receiver domain
Structure domains: Rossmann fold

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 4 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X29A
Spacegroup: P3221
Unit cell:
a: 49.797Å b: 49.797Å c: 111.05Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.218 0.218 0.255
Expression system: Escherichia coli BL21(DE3)

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