› 2qyt

X-ray diffraction
2.15Å resolution

Crystal structure of 2-dehydropantoate 2-reductase from Porphyromonas gingivalis W83

Released:
DOI: 10.2210/pdb2qyt/pdb
PDB entry 2qyt coloured by chain, front view.
PDB entry 2qyt coloured by chain, side view.
PDB entry 2qyt coloured by chain, top view.
Source organism: Porphyromonas gingivalis W83
Entry authors: Tan K, Wu R, Moy S, Joachimiak A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Reaction catalysed: 
(R)-pantoate + NADP(+) = 2-dehydropantoate + NADPH
Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181739 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
2-dehydropantoate 2-reductase Chain: A
Molecule details ›
Chain: A
Length: 317 amino acids
Theoretical weight: 35.67 KDa
Source organism: Porphyromonas gingivalis W83
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: Q7MT04 (Residues: 1-314; Coverage: 100%)
Gene names: PG_2205, panE
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand SO4 5 x SO4
Ligand EDO 5 x EDO
1 modified residue:
Ligand MSE 12 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: P41212
Unit cell:
a: 79.577Å b: 79.577Å c: 98.26Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.198 0.195 0.265
Expression system: Escherichia coli BL21

Quick links