› 2r0s

X-ray diffraction
1.8Å resolution

Crystal Structure of the Rsc4 tandem bromodomain

Released:
DOI: 10.2210/pdb2r0s/pdb
PDB entry 2r0s coloured by chain, front view.
PDB entry 2r0s coloured by chain, side view.
PDB entry 2r0s coloured by chain, top view.
Source organism: Saccharomyces cerevisiae
Primary publication:
Autoregulation of the rsc4 tandem bromodomain by gcn5 acetylation.
VanDemark AP, Kasten MM, Ferris E, Heroux A, Hill CP, Cairns BR
Mol Cell 27 817-28 (2007)
PMID: 17803945

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169685 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chromatin structure-remodeling complex subunit RSC4 Chain: A
Molecule details ›
Chain: A
Length: 285 amino acids
Theoretical weight: 34.08 KDa
Source organism: Saccharomyces cerevisiae
Expression system: Escherichia coli
UniProt:
  • Canonical: Q02206 (Residues: 36-320; Coverage: 46%)
Gene names: RSC4, YK107, YKR008W
Sequence domains: Bromodomain
Structure domains: Bromodomain-like

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 6 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: R32
Unit cell:
a: 95.899Å b: 95.899Å c: 233.519Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.216 0.176 0.218
Expression system: Escherichia coli

Quick links

Citations

36 review citations

The biology of chromatin remodeling complexes.
Clapier et al. (2009)
35 more

5 mentions without citation

Polybromo-1: the chromatin targeting subunit of the PBAF complex.
Thompson M. (2009)
4 more