› 2r18

X-ray diffraction
2.3Å resolution

Structural insights into the multifunctional protein VP3 of Birnaviruses

Released:
DOI: 10.2210/pdb2r18/pdb
PDB entry 2r18 coloured by chain, front view.
PDB entry 2r18 coloured by chain, side view.
PDB entry 2r18 coloured by chain, top view.
Source organism: Infectious bursal disease virus
Primary publication:
Structural insights into the multifunctional protein VP3 of birnaviruses.
Casañas A, Navarro A, Ferrer-Orta C, González D, Rodríguez JF, Verdaguer N
Structure 16 29-37 (2008)
PMID: 18184581

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-150407 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein VP3 Chain: A
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 15.79 KDa
Source organism: Infectious bursal disease virus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P25220 (Residues: 818-956; Coverage: 14%)
Sequence domains: Birnavirus VP3 protein
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID23-1
Spacegroup: P41212
Unit cell:
a: 68.316Å b: 68.316Å c: 71.295Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.226 0.222 0.264
Expression system: Spodoptera frugiperda

Quick links

Citations

1 review citation

The Infectious Pancreatic Necrosis Virus (IPNV) and its Virulence Determinants: What is Known and What Should be Known.
Dopazo CP. (2020)
24 other articles

3 mentions without citation

Identification, tissue distribution, and molecular modeling of novel human isoforms of the key enzyme in sialic acid synthesis, UDP-GlcNAc 2-epimerase/ManNAc kinase.
Yardeni et al. (2011)
2 more