› 2r2a

X-ray diffraction
1.82Å resolution

Crystal structure of N-terminal domain of zonular occludens toxin from Neisseria meningitidis

Released:
DOI: 10.2210/pdb2r2a/pdb
PDB entry 2r2a coloured by chain, front view.
PDB entry 2r2a coloured by chain, side view.
PDB entry 2r2a coloured by chain, top view.
Source organism: Neisseria meningitidis MC58
Entry authors: Osipiuk J, Patterson S, Wu R, Clancy S, Joachimiak A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-191664 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Zona occludens toxin N-terminal domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 199 amino acids
Theoretical weight: 23 KDa
Source organism: Neisseria meningitidis MC58
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9JRY6 (Residues: 1-196; Coverage: 53%)
Gene names: NMB1551, NMB1626
Sequence domains: Zonular occludens toxin (Zot)
Structure domains: P-loop containing nucleotide triphosphate hydrolases

Ligands and Environments

1 bound ligand:
Ligand SO4 2 x SO4
1 modified residue:
Ligand MSE 18 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID
Spacegroup: C2
Unit cell:
a: 134.976Å b: 48.258Å c: 95.894Å
α: 90° β: 134.31° γ: 90°
R-values:
R R work R free
0.178 0.176 0.214
Expression system: Escherichia coli BL21(DE3)

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