› 2rek

X-ray diffraction
1.86Å resolution

Crystal structure of tetR-family transcriptional regulator

Released:
DOI: 10.2210/pdb2rek/pdb
PDB entry 2rek coloured by chain, front view.
PDB entry 2rek coloured by chain, side view.
PDB entry 2rek coloured by chain, top view.
Source organism: Streptomyces coelicolor A3(2)
Entry authors: Dong A, Xu X, Gu J, Edwards AM, Joachimiak A, Savchenko A, Midwest Center for Structural Genomics (MCSG)

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189523 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
HTH tetR-type domain-containing protein Chains: A, B
Molecule details ›
Chains: A, B
Length: 199 amino acids
Theoretical weight: 20.91 KDa
Source organism: Streptomyces coelicolor A3(2)
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9ADD9 (Residues: 1-199; Coverage: 100%)
Gene names: SCBAC20F6.11c, SCO5068
Sequence domains:
Structure domains: Tetracycline Repressor, domain 2

Ligands and Environments

1 bound ligand:
Ligand ACT 1 x ACT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200, RIGAKU FR-E+ SUPERBRIGHT
Spacegroup: P212121
Unit cell:
a: 68.484Å b: 70.459Å c: 72.102Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.204 0.203 0.245
Expression system: Escherichia coli

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