› 2rjq

X-ray diffraction
2.6Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-193989 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
A disintegrin and metalloproteinase with thrombospondin motifs 5 Chain: A
Molecule details ›
Chain: A
Length: 378 amino acids
Theoretical weight: 41.65 KDa
Source organism: Homo sapiens
Expression system: Cricetulus griseus
UniProt:
  • Canonical: Q9UNA0 (Residues: 262-628; Coverage: 40%)
Gene names: ADAMTS11, ADAMTS5, ADMP2
Sequence domains:
Structure domains:

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
4 bound ligands:
Ligand ZN 2 x ZN
Ligand CL 2 x CL
Ligand CA 2 x CA
Ligand BAT 1 x BAT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 22-ID
Spacegroup: P3121
Unit cell:
a: 95.471Å b: 95.471Å c: 93.487Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.231 0.23 0.26
Expression system: Cricetulus griseus

Quick links

Citations

15 review citations

The ADAMTS (A Disintegrin and Metalloproteinase with Thrombospondin motifs) family.
Kelwick et al. (2015)
14 more

16 mentions without citation

ADAM and ADAMTS Family Proteins and Snake Venom Metalloproteinases: A Structural Overview.
Takeda S. (2016)
15 more