› 2rlj

Solution NMR

NMR Structure of Ebola fusion peptide in SDS micelles at pH 7

Released:
DOI: 10.2210/pdb2rlj/pdb
PDB entry 2rlj coloured by chain, ensemble of 20 models, front view.
PDB entry 2rlj coloured by chain, ensemble of 20 models, side view.
PDB entry 2rlj coloured by chain, ensemble of 20 models, top view.
Source organism: Zaire ebolavirus
Primary publication:
Structure of the Ebola fusion peptide in a membrane-mimetic environment and the interaction with lipid rafts.
Freitas MS, Gaspar LP, Lorenzoni M, Almeida FCL, Tinoco LW, Almeida MS, Maia LF, Degrève L, Valente AP, Silva JL
J Biol Chem 282 27306-27314 (2007)
PMID: 17545161

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-170172 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GP2 Chain: A
Molecule details ›
Chain: A
Length: 16 amino acids
Theoretical weight: 1.57 KDa
Source organism: Zaire ebolavirus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q05320 (Residues: 524-539; Coverage: 3%)
Gene name: GP

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

8 review citations

Structures and mechanisms of viral membrane fusion proteins: multiple variations on a common theme.
White et al. (2008)
7 more

3 mentions without citation

Measuring the strength of interaction between the Ebola fusion peptide and lipid rafts: implications for membrane fusion and virus infection.
Freitas et al. (2011)
2 more