› 2rnq

Solution NMR

Solution structure of the C-terminal acidic domain of TFIIE alpha

Released:
DOI: 10.2210/pdb2rnq/pdb
PDB entry 2rnq coloured by chain, ensemble of 20 models, front view.
PDB entry 2rnq coloured by chain, ensemble of 20 models, side view.
PDB entry 2rnq coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural insight into the TFIIE-TFIIH interaction: TFIIE and p53 share the binding region on TFIIH.
Okuda M, Tanaka A, Satoh M, Mizuta S, Takazawa M, Ohkuma Y, Nishimura Y
EMBO J 27 1161-71 (2008)
PMID: 18354501

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151350 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
General transcription factor IIE subunit 1 Chain: A
Molecule details ›
Chain: A
Length: 64 amino acids
Theoretical weight: 7.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P29083 (Residues: 378-439; Coverage: 14%)
Gene names: GTF2E1, TF2E1
Sequence domains: C-terminal general transcription factor TFIIE alpha
Structure domains: Helix Hairpins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DGSA-distance geometry simulated annealing, simulated annealing
Expression system: Escherichia coli

Quick links

Citations

5 review citations

Structural basis of transcription initiation by RNA polymerase II.
Sainsbury et al. (2015)
4 more

2 mentions without citation

Structural insight into the TFIIE-TFIIH interaction: TFIIE and p53 share the binding region on TFIIH.
Okuda et al. (2008)
1 more