› 2rov

Solution NMR

The split PH domain of ROCK II

Released:
DOI: 10.2210/pdb2rov/pdb
PDB entry 2rov coloured by chain, ensemble of 20 models, front view.
PDB entry 2rov coloured by chain, ensemble of 20 models, side view.
PDB entry 2rov coloured by chain, ensemble of 20 models, top view.
Source organism: Rattus norvegicus
Entry authors: Wen W, Zhang M

Function and Biology Details

Reaction catalysed: 
ATP + a protein = ADP + a phosphoprotein
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178974 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Rho-associated protein kinase 2 Chain: A
Molecule details ›
Chain: A
Length: 117 amino acids
Theoretical weight: 13.72 KDa
Source organism: Rattus norvegicus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q62868 (Residues: 1151-1351; Coverage: 8%)
Gene name: Rock2
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli

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