› 2rpp

Solution NMR

Solution structure of Tandem zinc finger domain 12 in Muscleblind-like protein 2

Released:
DOI: 10.2210/pdb2rpp/pdb
PDB entry 2rpp coloured by chain, ensemble of 20 models, front view.
PDB entry 2rpp coloured by chain, ensemble of 20 models, side view.
PDB entry 2rpp coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the RNA binding domain in the human muscleblind-like protein 2.
He F, Dang W, Abe C, Tsuda K, Inoue M, Watanabe S, Kobayashi N, Kigawa T, Matsuda T, Yabuki T, Aoki M, Seki E, Harada T, Tomabechi Y, Terada T, Shirouzu M, Tanaka A, Güntert P, Muto Y, Yokoyama S
Protein Sci 18 80-91 (2009)
PMID: 19177353

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-178456 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Muscleblind-like protein 2 Chain: A
Molecule details ›
Chain: A
Length: 89 amino acids
Theoretical weight: 9.83 KDa
Source organism: Homo sapiens
Expression system: CELL-FREE SYNTHESIS
UniProt:
  • Canonical: Q5VZF2 (Residues: 7-82; Coverage: 20%)
Gene names: MBLL, MBLL39, MBNL2, MLP1
Sequence domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics, RESTRAINTED MOLECULAR DYNAMICS
Expression system: CELL-FREE SYNTHESIS

Quick links

Citations

18 citation in other articles

Aberrant alternative splicing and extracellular matrix gene expression in mouse models of myotonic dystrophy.
Du et al. (2010)
17 more

4 mentions without citation

Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T.
Park et al. (2017)
3 more