› 2rqy

Solution NMR

Solution structure and dynamics of mouse ARMET

Released:
DOI: 10.2210/pdb2rqy/pdb
PDB entry 2rqy coloured by chain, ensemble of 10 models, front view.
PDB entry 2rqy coloured by chain, ensemble of 10 models, side view.
PDB entry 2rqy coloured by chain, ensemble of 10 models, top view.
Source organism: Mus musculus
Primary publication:
Solution structure and dynamics of mouse ARMET.
Hoseki J, Sasakawa H, Yamaguchi Y, Maeda M, Kubota H, Kato K, Nagata K
FEBS Lett 584 1536-42 (2010)
PMID: 20214902

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190021 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Mesencephalic astrocyte-derived neurotrophic factor Chain: A
Molecule details ›
Chain: A
Length: 171 amino acids
Theoretical weight: 19.93 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9CXI5 (Residues: 22-179; Coverage: 100%)
Gene names: Armet, Manf
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

4 review citations

Unconventional neurotrophic factors CDNF and MANF: Structure, physiological functions and therapeutic potential.
Lindahl et al. (2017)
3 more

1 mention without citation

Mesencephalic astrocyte-derived neurotrophic factor (MANF) has a unique mechanism to rescue apoptotic neurons.
Hellman et al. (2011)