› 2rr9

Solution NMR

The solution structure of the K63-Ub2:tUIMs complex

Released:
DOI: 10.2210/pdb2rr9/pdb
PDB entry 2rr9 coloured by chain, ensemble of 20 models, front view.
PDB entry 2rr9 coloured by chain, ensemble of 20 models, side view.
PDB entry 2rr9 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Entry authors: Sekiyama N, Jee J, Isogai S, Akagi K, Huang T, Ariyoshi M, Tochio H, Shirakawa M

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
hetero trimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-143440 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ubiquitin Chains: A, B
Molecule details ›
Chains: A, B
Length: 76 amino acids
Theoretical weight: 8.58 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P0CG48 (Residues: 609-684; Coverage: 11%)
Gene name: UBC
Sequence domains: Ubiquitin family
Structure domains: Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
BRCA1-A complex subunit RAP80 Chain: C
Molecule details ›
Chain: C
Length: 46 amino acids
Theoretical weight: 5.32 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q96RL1 (Residues: 79-124; Coverage: 6%)
Gene names: RAP80, RXRIP110, UIMC1
Sequence domains: RAP80 N-terminal ubiquitin interaction motif

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics
Expression system: Escherichia coli

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