› 2rrh

Solution NMR

NMR structure of vasoactive intestinal peptide in Methanol

Released:
DOI: 10.2210/pdb2rrh/pdb
PDB entry 2rrh coloured by chain, ensemble of 20 models, front view.
PDB entry 2rrh coloured by chain, ensemble of 20 models, side view.
PDB entry 2rrh coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Structural difference of vasoactive intestinal peptide in two distinct membrane-mimicking environments.
Umetsu Y, Tenno T, Goda N, Shirakawa M, Ikegami T, Hiroaki H
Biochim Biophys Acta 1814 724-30 (2011)
PMID: 21439408

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134166 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Vasoactive intestinal peptide Chain: A
Molecule details ›
Chain: A
Length: 29 amino acids
Theoretical weight: 3.39 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01282 (Residues: 125-153; Coverage: 19%)
Gene name: VIP
Sequence domains: Peptide hormone

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli

Quick links

Citations

9 review citations

Recent advances in vasoactive intestinal peptide physiology and pathophysiology: focus on the gastrointestinal system.
Iwasaki et al. (2019)
8 more

3 mentions without citation

Therapeutic efficacy of stable analogues of vasoactive intestinal peptide against pathogens.
Campos-Salinas et al. (2014)
2 more