› 2rrm

Solution NMR

Interplay between phosphatidyl-inositol-phosphates and claudins upon binding to the 1st PDZ domain of zonula occludens 1

Released:
DOI: 10.2210/pdb2rrm/pdb
PDB entry 2rrm coloured by chain, ensemble of 20 models, front view.
PDB entry 2rrm coloured by chain, ensemble of 20 models, side view.
PDB entry 2rrm coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Primary publication:
1H, 13C, and 15N resonance assignment of the first PDZ domain of mouse ZO-1.
Umetsu Y, Goda N, Taniguchi R, Satomura K, Ikegami T, Furuse M, Hiroaki H
Biomol NMR Assign 5 207-10 (2011)
PMID: 21431884

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-153883 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tight junction protein ZO-1 Chain: A
Molecule details ›
Chain: A
Length: 100 amino acids
Theoretical weight: 10.82 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P39447 (Residues: 18-110; Coverage: 5%)
Gene names: Tjp1, Zo1
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 83%
Refinement method: simulated annealing
Expression system: Escherichia coli

Quick links

Citations

4 citation in other articles

Opposing Effect of Naringenin and Quercetin on the Junctional Compartment of MDCK II Cells to Modulate the Tight Junction.
Nakashima et al. (2020)
3 more

8 mentions without citation

Lineage-specific loss and divergence of functionally linked genes in eukaryotes.
Aravind et al. (2000)
7 more