› 2rs6

Solution NMR

Solution structure of the N-terminal dsRBD from RNA helicase A

Released:
DOI: 10.2210/pdb2rs6/pdb
PDB entry 2rs6 coloured by chain, ensemble of 20 models, front view.
PDB entry 2rs6 coloured by chain, ensemble of 20 models, side view.
PDB entry 2rs6 coloured by chain, ensemble of 20 models, top view.
Source organism: Mus musculus
Primary publication:
Solution structures of the double-stranded RNA-binding domains from RNA helicase A.
Nagata T, Tsuda K, Kobayashi N, Shirouzu M, Kigawa T, Güntert P, Yokoyama S, Muto Y
Proteins 80 1699-706 (2012)
PMID: 22454253

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O = ADP + phosphate
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130675 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
ATP-dependent RNA helicase A Chain: A
Molecule details ›
Chain: A
Length: 99 amino acids
Theoretical weight: 10.73 KDa
Source organism: Mus musculus
Expression system: cell-free protein synthesis
UniProt:
  • Canonical: O70133 (Residues: 4-89; Coverage: 6%)
Gene names: Ddx9, Dhx9
Sequence domains: Double-stranded RNA binding motif
Structure domains: Double Stranded RNA Binding Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 93%
Refinement method: simulated annealing, torsion angle dynamics
Expression system: cell-free protein synthesis

Quick links

Citations

1 review citation

The biology of DHX9 and its potential as a therapeutic target.
Lee et al. (2016)
4 other articles

1 mention without citation

RNA recognition by double-stranded RNA binding domains: a matter of shape and sequence.
Masliah et al. (2013)