› 2rsw

Solution NMR

NMR structure, Localization and Vesicle fusion of Chikungunya virus Fusion peptide

Released:
DOI: 10.2210/pdb2rsw/pdb
PDB entry 2rsw coloured by chain, ensemble of 20 models, front view.
PDB entry 2rsw coloured by chain, ensemble of 20 models, side view.
PDB entry 2rsw coloured by chain, ensemble of 20 models, top view.
Source organism: Chikungunya virus strain S27-African prototype
Primary publication:
NMR structure, localization, and vesicle fusion of Chikungunya virus fusion peptide.
Mohanram H, Nip A, Domadia PN, Bhunia A, Bhattacharjya S
Biochemistry 51 7863-72 (2012)
PMID: 22978677

Function and Biology Details

Reaction catalysed: 
Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-|-Ser- bond.
Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185026 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Spike glycoprotein E1 Chain: A
Molecule details ›
Chain: A
Length: 18 amino acids
Theoretical weight: 2.07 KDa
Source organism: Chikungunya virus strain S27-African prototype
Expression system: Not provided
UniProt:
  • Canonical: Q8JUX5 (Residues: 893-910; Coverage: 1%)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 31%
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

3 review citations

The three lives of viral fusion peptides.
Apellániz et al. (2014)
2 more