Function and Biology Details
Biochemical function:
- not assigned
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152450 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
DNA repair protein complementing XP-C cells
Molecule details ›
Chain: A
Length: 52 amino acids
Theoretical weight: 5.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Length: 52 amino acids
Theoretical weight: 5.93 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical:
Q01831 (Residues: 109-156; Coverage: 5%)
General transcription factor IIH subunit 1
Molecule details ›
Chain: B
Length: 110 amino acids
Theoretical weight: 12.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
Sequence domains: TFIIH p62 subunit, N-terminal domain
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Length: 110 amino acids
Theoretical weight: 12.45 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
- Canonical: P32780 (Residues: 1-108; Coverage: 20%)
Sequence domains: TFIIH p62 subunit, N-terminal domain
Structure domains: Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
Chemical shift assignment:
89%
Refinement method:
DGSA-distance geometry simulated annealing
Expression system: Escherichia coli
