› 2sak

X-ray diffraction
1.8Å resolution

STAPHYLOKINASE (SAKSTAR VARIANT)

Released:
DOI: 10.2210/pdb2sak/pdb
PDB entry 2sak coloured by chain, front view.
PDB entry 2sak coloured by chain, side view.
PDB entry 2sak coloured by chain, top view.
Source organism: Staphylococcus aureus
Primary publication:
Three-dimensional structure of staphylokinase, a plasminogen activator with therapeutic potential.
Rabijns A, De Bondt HL, De Ranter C
Nat Struct Biol 4 357-60 (1997)
PMID: 9145104

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-159507 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Staphylokinase Chain: A
Molecule details ›
Chain: A
Length: 121 amino acids
Theoretical weight: 13.9 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: P68802 (Residues: 43-163; Coverage: 89%)
Gene name: sak
Sequence domains: Staphylokinase/Streptokinase family
Structure domains: Ubiquitin-like (UB roll)

Ligands and Environments

1 bound ligand:
Ligand TRS 1 x TRS
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup: C2
Unit cell:
a: 60.6Å b: 43.73Å c: 54.27Å
α: 90° β: 115.63° γ: 90°
R-values:
R R work R free
0.181 0.181 0.237

Quick links

Citations

7 review citations

Bacterial plasminogen activators and receptors.
Lähteenmäki et al. (2001)
6 more

15 mentions without citation

The natural history of ubiquitin and ubiquitin-related domains.
Burroughs et al. (2012)
14 more