› 2sh1

Solution NMR

SOLUTION STRUCTURE OF NEUROTOXIN I FROM THE SEA ANEMONE STICHODACTYLA HELIANTHUS. A NUCLEAR MAGNETIC RESONANCE, DISTANCE GEOMETRY AND RESTRAINED MOLECULAR DYNAMICS STUDY

Released:
DOI: 10.2210/pdb2sh1/pdb
PDB entry 2sh1 coloured by chain, ensemble of 8 models, front view.
PDB entry 2sh1 coloured by chain, ensemble of 8 models, side view.
PDB entry 2sh1 coloured by chain, ensemble of 8 models, top view.
Source organism: Stichodactyla helianthus
Primary publication:
Solution structure of neurotoxin I from the sea anemone Stichodactyla helianthus. A nuclear magnetic resonance, distance geometry, and restrained molecular dynamics study.
Fogh RH, Kem WR, Norton RS
J Biol Chem 265 13016-28 (1990)
PMID: 1973932

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-148677 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Delta-stichotoxin-She1a Chain: A
Molecule details ›
Chain: A
Length: 48 amino acids
Theoretical weight: 5.15 KDa
Source organism: Stichodactyla helianthus
Expression system: Not provided
UniProt:
  • Canonical: P19651 (Residues: 1-48; Coverage: 100%)
Sequence domains: Anenome neurotoxin
Structure domains: Anthopleurin-A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

10 review citations

Structure and structure-function relationships of sea anemone proteins that interact with the sodium channel.
Norton RS. (1991)
9 more

1 mention without citation

New Insights into the Type II Toxins from the Sea Anemone Heteractis crispa.
Kalina et al. (2020)