› 2siv

X-ray diffraction
2.2Å resolution

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
hetero hexamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-176034 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Envelope glycoprotein gp160 Chains: A, C, E
Molecule details ›
Chains: A, C, E
Length: 38 amino acids
Theoretical weight: 4.22 KDa
Source organism: Simian immunodeficiency virus
Expression system: Not provided
UniProt:
  • Canonical: Q8AKX0 (Residues: 162-197; Coverage: 16%)
Gene name: env
Sequence domains: Retroviral envelope protein
Envelope glycoprotein Chains: B, D, F
Molecule details ›
Chains: B, D, F
Length: 36 amino acids
Theoretical weight: 4.31 KDa
Source organism: Simian immunodeficiency virus
Expression system: Not provided
UniProt:
  • Canonical: Q52SW3 (Residues: 66-100; Coverage: 22%)
Gene name: env

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P212121
Unit cell:
a: 55.722Å b: 57.713Å c: 66.513Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.211 0.211 0.288
Expression system: Not provided

Quick links

Citations

19 review citations

Mechanisms of viral membrane fusion and its inhibition.
Eckert et al. (2001)
18 more

4 mentions without citation

HIV: cell binding and entry.
Wilen et al. (2012)
3 more