› 2snv

X-ray diffraction
2.8Å resolution

THE REFINED STRUCTURE OF SINDBIS VIRUS CORE PROTEIN IN COMPARISON WITH OTHER CHYMOTRYPSIN-LIKE SERINE PROTEINASE STRUCTURES

Released:
DOI: 10.2210/pdb2snv/pdb
Model geometry
Fit model/data
Data not deposited
PDB entry 2snv coloured by chain, front view.
PDB entry 2snv coloured by chain, side view.
PDB entry 2snv coloured by chain, top view.
Source organism: Sindbis virus
Primary publication:
Refined structure of Sindbis virus core protein and comparison with other chymotrypsin-like serine proteinase structures.
Tong L, Wengler G, Rossmann MG
J Mol Biol 230 228-47 (1993)
PMID: 8450538

Function and Biology Details

Reaction catalysed: 
Autocatalytic release of the core protein from the N-terminus of the togavirus structural polyprotein by hydrolysis of a -Trp-|-Ser- bond.
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136788 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein Chain: A
Molecule details ›
Chain: A
Length: 151 amino acids
Theoretical weight: 16.55 KDa
Source organism: Sindbis virus
Expression system: Not provided
UniProt:
  • Canonical: P03316 (Residues: 114-264; Coverage: 12%)
Sequence domains: Alphavirus core protein
Structure domains: Trypsin-like serine proteases

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
Spacegroup: P43212
Unit cell:
a: 57Å b: 57Å c: 109.8Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.2 0.2 not available
Expression system: Not provided

Quick links

Citations

11 review citations

The alphaviruses: gene expression, replication, and evolution.
Strauss et al. (1994)
10 more

4 mentions without citation

Tools for integrated sequence-structure analysis with UCSF Chimera.
Meng et al. (2006)
3 more