› 2tob

Solution NMR

SOLUTION STRUCTURE OF THE TOBRAMYCIN-RNA APTAMER COMPLEX, NMR, 13 STRUCTURES

Released:
DOI: 10.2210/pdb2tob/pdb
PDB entry 2tob coloured by chain, ensemble of 13 models, front view.
PDB entry 2tob coloured by chain, ensemble of 13 models, side view.
PDB entry 2tob coloured by chain, ensemble of 13 models, top view.
Source organism: synthetic construct
Primary publication:
Solution structure of the tobramycin-RNA aptamer complex.
Jiang L, Patel DJ
Nat Struct Biol 5 769-74 (1998)
PMID: 9731769

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-196591 (preferred)
Entry contents:
1 distinct RNA molecule
Macromolecule:
RNA (5'-R(*AP*CP*UP*UP*GP*GP*UP*UP*UP*AP*GP*GP*UP*AP*AP*UP*GP*AP*GP*U)-3') Chain: A
Molecule details ›
Chain: A
Length: 20 nucleotides
Theoretical weight: 6.43 KDa
Source organism: synthetic construct
Expression system: Not provided

Ligands and Environments

3 bound ligands:
Ligand TOA 1 x TOA
Ligand TOC 1 x TOC
Ligand 2TB 1 x 2TB
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE-RESTRAINED MOLECULAR DYNAMICS
Expression system: Not provided

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Citations

18 review citations

In vitro selection of functional nucleic acids.
Wilson et al. (1999)
17 more

6 mentions without citation

Selection and Biosensor Application of Aptamers for Small Molecules.
Pfeiffer et al. (2016)
5 more