› 2tss

X-ray diffraction
2.05Å resolution

TOXIC SHOCK SYNDROME TOXIN-1 FROM STAPHYLOCOCCUS AUREUS: ORTHORHOMBICC222(1) CRYSTAL FORM

Released:
DOI: 10.2210/pdb2tss/pdb
PDB entry 2tss coloured by chain, front view.
PDB entry 2tss coloured by chain, side view.
PDB entry 2tss coloured by chain, top view.
Source organism: Staphylococcus aureus
Primary publication:
Refined structures of three crystal forms of toxic shock syndrome toxin-1 and of a tetramutant with reduced activity.
Prasad GS, Radhakrishnan R, Mitchell DT, Earhart CA, Dinges MM, Cook WJ, Schlievert PM, Ohlendorf DH
Protein Sci 6 1220-7 (1997)
PMID: 9194182

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-139296 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Toxic shock syndrome toxin-1 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 194 amino acids
Theoretical weight: 22.1 KDa
Source organism: Staphylococcus aureus
UniProt:
  • Canonical: P06886 (Residues: 41-234; Coverage: 100%)
Gene name: tst
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH2R
Spacegroup: C2221
Unit cell:
a: 108.7Å b: 177.5Å c: 97.6Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.154 0.154 not available

Quick links

Citations

5 review citations

Exotoxins of Staphylococcus aureus.
Dinges et al. (2000)
4 more

4 mentions without citation

Identification of a novel gene cluster encoding staphylococcal exotoxin-like proteins: characterization of the prototypic gene and its protein product, SET1.
Williams et al. (2000)
3 more