Function and Biology Details
Reaction catalysed:
leukotriene C4 = leukotriene A4 + glutathione.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:
Structure analysis Details
Assembly composition:
homo trimer (preferred)
Assembly name:
Leukotriene C4 synthase (preferred)
PDBe Complex ID:
PDB-CPX-172606 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Leukotriene C4 synthase
Molecule details ›
Chain: A
Length: 156 amino acids
Theoretical weight: 17.41 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
Sequence domains: MAPEG family
Structure domains: Membrane associated eicosanoid/glutathione metabolism-like domain
Length: 156 amino acids
Theoretical weight: 17.41 KDa
Source organism: Homo sapiens
Expression system: Komagataella pastoris
UniProt:
- Canonical:
Q16873 (Residues: 2-150; Coverage: 99%)
Sequence domains: MAPEG family
Structure domains: Membrane associated eicosanoid/glutathione metabolism-like domain
Ligands and Environments
Experiments and Validation Details
wwPDB Validation report is not available for this entry.
X-ray source:
ESRF BEAMLINE ID23-2
Spacegroup:
F23
Expression system: Komagataella pastoris
