› 2uyg

X-ray diffraction
2.2Å resolution

Crystallogaphic structure of the typeII 3-Dehydroquinase from Thermus Thermophilus

Released:
DOI: 10.2210/pdb2uyg/pdb
PDB entry 2uyg coloured by chain, front view.
PDB entry 2uyg coloured by chain, side view.
PDB entry 2uyg coloured by chain, top view.
Source organism: Thermus thermophilus HB8
Entry authors: Utsunomiya H, Agari Y, Imagawa T, Tsuge H

Function and Biology Details

Reaction catalysed: 
3-dehydroquinate = 3-dehydroshikimate + H(2)O
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo dodecamer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-177965 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
3-dehydroquinate dehydratase Chains: A, B, C, D, E, F, G, H, I, J, K, L
Molecule details ›
Chains: A, B, C, D, E, F, G, H, I, J, K, L
Length: 149 amino acids
Theoretical weight: 16.47 KDa
Source organism: Thermus thermophilus HB8
Expression system: Escherichia coli B
UniProt:
  • Canonical: Q5SIL5 (Residues: 1-149; Coverage: 100%)
Gene names: TTHA1354, aroQ
Sequence domains: Dehydroquinase class II
Structure domains: Dehydroquinase, class II

Ligands and Environments

1 bound ligand:
Ligand GOL 12 x GOL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SPRING-8 BEAMLINE BL26B2
Spacegroup: P212121
Unit cell:
a: 84.085Å b: 151.586Å c: 159.949Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.232 0.23 0.277
Expression system: Escherichia coli B

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