› 2uyy

X-ray diffraction
2.5Å resolution

Structure of the cytokine-like nuclear factor n-pac

Released:
DOI: 10.2210/pdb2uyy/pdb
PDB entry 2uyy coloured by chain, front view.
PDB entry 2uyy coloured by chain, side view.
PDB entry 2uyy coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Tickle J, Pilka ES, Bunkoczi G, Berridge G, Smee C, Kavanagh KL, Hozjan V, Niesen FH, Papagrigoriou E, Pike ACW, Turnbull A, Arrowsmith CH, Edwards A, Sundstrom M, Weigelt J, von Delft F, Oppermann U

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
homo tetramer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-175409 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cytokine-like nuclear factor N-PAC Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 316 amino acids
Theoretical weight: 34.09 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q49A26 (Residues: 261-553; Coverage: 53%)
Gene names: GLYR1, HIBDL, NDF, NP60, NPAC
Sequence domains:
Structure domains:

Ligands and Environments

2 bound ligands:
Ligand K 4 x K
Ligand NA7 2 x NA7
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: R3
Unit cell:
a: 134.18Å b: 134.18Å c: 261.463Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.172 0.17 0.211
Expression system: Escherichia coli BL21(DE3)

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