› 2v0f

Solution NMR

BRK domain from human CHD7

Released:
DOI: 10.2210/pdb2v0f/pdb
PDB entry 2v0f coloured by chain, ensemble of 20 models, front view.
PDB entry 2v0f coloured by chain, ensemble of 20 models, side view.
PDB entry 2v0f coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the BRK domains from CHD7.
Allen MD, Religa TL, Freund SM, Bycroft M
J Mol Biol 371 1135-40 (2007)
PMID: 17603073

Function and Biology Details

Reaction catalysed: 
ATP + H(2)O = ADP + phosphate
Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-192835 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Chromodomain-helicase-DNA-binding protein 7 Chain: A
Molecule details ›
Chain: A
Length: 87 amino acids
Theoretical weight: 9.56 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9P2D1 (Residues: 2631-2715; Coverage: 3%)
Gene names: CHD7, KIAA1416
Sequence domains: BRK domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: CNS
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

6 review citations

The BRG1 transcriptional coregulator.
Trotter et al. (2008)
5 more

1 mention without citation

The dipeptidyl peptidase IV inhibitors vildagliptin and K-579 inhibit a phospholipase C: a case of promiscuous scaffolds in proteins.
Chakraborty et al. (2013)