› 2v4x

X-ray diffraction
1.5Å resolution

Crystal Structure of Jaagsiekte Sheep Retrovirus Capsid N-terminal domain

Released:
DOI: 10.2210/pdb2v4x/pdb
PDB entry 2v4x coloured by chain, front view.
PDB entry 2v4x coloured by chain, side view.
PDB entry 2v4x coloured by chain, top view.
Source organism: Jaagsiekte sheep retrovirus
Primary publication:
Structure of the capsid amino-terminal domain from the betaretrovirus, Jaagsiekte sheep retrovirus.
Mortuza GB, Goldstone DC, Pashley C, Haire LF, Palmarini M, Taylor WR, Stoye JP, Taylor IA
J Mol Biol 386 1179-92 (2009)
PMID: 19007792

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152040 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Capsid protein p27 Chain: A
Molecule details ›
Chain: A
Length: 140 amino acids
Theoretical weight: 16.12 KDa
Source organism: Jaagsiekte sheep retrovirus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P31622 (Residues: 257-388; Coverage: 22%)
Gene name: gag
Sequence domains: gag protein p24 N-terminal domain
Structure domains: Human Immunodeficiency Virus Type 1 Capsid Protein

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 2 x MSE

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX14.1
Spacegroup: P21
Unit cell:
a: 29.595Å b: 57.826Å c: 40.927Å
α: 90° β: 109.17° γ: 90°
R-values:
R R work R free
0.152 0.15 0.185
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

1 review citation

Assembly and architecture of HIV.
Ganser-Pornillos et al. (2012)
16 other articles

3 mentions without citation

Multiple sites in the N-terminal half of simian immunodeficiency virus capsid protein contribute to evasion from rhesus monkey TRIM5α-mediated restriction.
Kono et al. (2010)
2 more