2vg0

X-ray diffraction
1.7Å resolution

Rv1086 citronellyl pyrophosphate complex

Released:
Source organism: Mycobacterium tuberculosis
Primary publication:
The structural basis of chain length control in Rv1086.
J Mol Biol 381 129-40 (2008)
PMID: 18597781

Function and Biology Details

Reaction catalysed:
Geranyl diphosphate + isopentenyl diphosphate = diphosphate + (2Z,6E)-farnesyl diphosphate
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-161409 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
(2Z,6E)-farnesyl diphosphate synthase Chains: A, B
Molecule details ›
Chains: A, B
Length: 227 amino acids
Theoretical weight: 25.26 KDa
Source organism: Mycobacterium tuberculosis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P9WFF5 (Residues: 30-256; Coverage: 87%)
Gene names: MTV017.39, Rv1086
Sequence domains: Putative undecaprenyl diphosphate synthase
Structure domains: Decaprenyl diphosphate synthase-like

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-3
Spacegroup: P212121
Unit cell:
a: 58.517Å b: 73.541Å c: 102.561Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.176 0.173 0.215
Expression system: Escherichia coli BL21(DE3)