› 2vrf

X-ray diffraction
2Å resolution

CRYSTAL STRUCTURE OF THE HUMAN BETA-2-SYNTROPHIN PDZ DOMAIN

Released:
DOI: 10.2210/pdb2vrf/pdb
PDB entry 2vrf coloured by chain, front view.
PDB entry 2vrf coloured by chain, side view.
PDB entry 2vrf coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Sun Z, Roos AK, Pike ACW, Pilka ES, Cooper C, Elkins JM, Murray J, Arrowsmith CH, Doyle D, Edwards A, von Delft F, Bountra C, Oppermann U

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assemblies composition:
monomeric (preferred)
homo dimer
Assembly name:
PDBe Complex ID:
PDB-CPX-171678 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-2-syntrophin Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 95 amino acids
Theoretical weight: 10.35 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q13425 (Residues: 112-200; Coverage: 17%)
Gene names: D16S2531E, SNT2B2, SNTB2, SNTL
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

1 bound ligand:
Ligand EDO 3 x EDO
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P21
Unit cell:
a: 56.687Å b: 29.503Å c: 128.382Å
α: 90° β: 95.78° γ: 90°
R-values:
R R work R free
0.186 0.184 0.247
Expression system: Escherichia coli BL21(DE3)

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