› 2vry

X-ray diffraction
1.87Å resolution

Mouse Neuroglobin with heme iron in the reduced ferrous state

Released:
DOI: 10.2210/pdb2vry/pdb
PDB entry 2vry coloured by chain, front view.
PDB entry 2vry coloured by chain, side view.
PDB entry 2vry coloured by chain, top view.
Source organism: Mus musculus
Primary publication:
An X-ray diffraction and X-ray absorption spectroscopy joint study of neuroglobin.
Arcovito A, Moschetti T, D'Angelo P, Mancini G, Vallone B, Brunori M, Della Longa S
Arch Biochem Biophys 475 7-13 (2008)
PMID: 18406335

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assemblies composition:
homo hexamer
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190170 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Neuroglobin Chain: A
Molecule details ›
Chain: A
Length: 154 amino acids
Theoretical weight: 17.31 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9ER97 (Residues: 1-151; Coverage: 100%)
Gene name: Ngb
Sequence domains: Globin
Structure domains: Globins

Ligands and Environments

2 bound ligands:
Ligand HEM 1 x HEM
Ligand SO4 2 x SO4
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: R32
Unit cell:
a: 87.92Å b: 87.92Å c: 113.646Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.187 0.185 0.217
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Neuroglobin: From structure to function in health and disease.
Ascenzi et al. (2016)
3 more

2 mentions without citation

Changes in dynamics upon oligomerization regulate substrate binding and allostery in amino acid kinase family members.
Marcos et al. (2011)
1 more