› 2vvg

X-ray diffraction
1.6Å resolution

Crystal Structure of the G.intestinalis Kinesin 2 GiKIN2a Motor Domain

Released:
DOI: 10.2210/pdb2vvg/pdb
PDB entry 2vvg coloured by chain, front view.
PDB entry 2vvg coloured by chain, side view.
PDB entry 2vvg coloured by chain, top view.
Source organism: Giardia intestinalis
Primary publication:
High-resolution crystal structure and in vivo function of a kinesin-2 homologue in Giardia intestinalis.
Hoeng JC, Dawson SC, House SA, Sagolla MS, Pham JK, Mancuso JJ, Löwe J, Cande WZ
Mol Biol Cell 19 3124-37 (2008)
PMID: 18463165

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-108584 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kinesin-2a Chains: A, B
Molecule details ›
Chains: A, B
Length: 350 amino acids
Theoretical weight: 38.64 KDa
Source organism: Giardia intestinalis
UniProt:
  • Canonical: A8BKD1 (Residues: 1-350; Coverage: 49%)
Gene names: GL50803_0017333, GL50803_17333, kin-2a
Sequence domains: Kinesin motor domain
Structure domains: Kinesin motor domain

Ligands and Environments

2 bound ligands:
Ligand ADP 2 x ADP
Ligand MG 2 x MG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE ID14-3
Spacegroup: P1
Unit cell:
a: 44.875Å b: 48.223Å c: 72.021Å
α: 89.3° β: 87.52° γ: 84.29°
R-values:
R R work R free
0.203 0.203 0.224

Quick links

Citations

13 review citations

Ultrastructure of cilia and flagella - back to the future!
Fisch et al. (2011)
12 more

2 mentions without citation

Kinesin-2 motors: Kinetics and biophysics.
Gilbert et al. (2018)
1 more