› 2vwr

X-ray diffraction
1.3Å resolution

Crystal structure of the second pdz domain of numb-binding protein 2

Released:
DOI: 10.2210/pdb2vwr/pdb
PDB entry 2vwr coloured by chain, front view.
PDB entry 2vwr coloured by chain, side view.
PDB entry 2vwr coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Roos AK, Guo K, Burgess-Brown N, Yue WW, Elkins JM, Pike ACW, Filippakopoulos P, Arrowsmith CH, Wikstom M, Edwards A, von Delft F, Bountra C, Doyle D, Oppermann U

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-185381 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ligand of Numb protein X 2 Chain: A
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 10.31 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q8N448 (Residues: 336-425; Coverage: 13%)
Gene names: LNX2, PDZRN1
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: C2
Unit cell:
a: 63.773Å b: 38.643Å c: 38.186Å
α: 90° β: 117.22° γ: 90°
R-values:
R R work R free
0.136 0.134 0.177
Expression system: Escherichia coli BL21(DE3)

Quick links