› 2vxe

Solution NMR

SOLUTION STRUCTURE OF THE LSM DOMAIN OF DROSOPHILA MELANOGASTER TRAL (TRAILER HITCH)

Released:
DOI: 10.2210/pdb2vxe/pdb
PDB entry 2vxe coloured by chain, ensemble of 24 models, front view.
PDB entry 2vxe coloured by chain, ensemble of 24 models, side view.
PDB entry 2vxe coloured by chain, ensemble of 24 models, top view.
Source organism: Drosophila melanogaster
Primary publication:
Similar modes of interaction enable Trailer Hitch and EDC3 to associate with DCP1 and Me31B in distinct protein complexes.
Tritschler F, Eulalio A, Helms S, Schmidt S, Coles M, Weichenrieder O, Izaurralde E, Truffault V
Mol Cell Biol 28 6695-708 (2008)
PMID: 18765641

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-194304 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Trailer hitch, isoform B Chain: A
Molecule details ›
Chain: A
Length: 88 amino acids
Theoretical weight: 9.78 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli K-12
UniProt:
  • Canonical: Q9VTZ0 (Residues: 1-84; Coverage: 13%)
Gene names: BEST:GH08269, CG10686, DmLSm15, Dmel\CG10686, Dmel_CG10686, LSm15, Lsm15, Scd6p, TRAL, Tral, anon-EST:Posey139, anon-WO0172774.89, anon-WO02059370.24, p67, p70, tral
Sequence domains: Scd6-like Sm domain
Structure domains: SH3 type barrels.

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: XPLOR
Expression system: Escherichia coli K-12

Quick links

Citations

11 review citations

Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?
Burghes et al. (2009)
10 more

3 mentions without citation

The role of disordered protein regions in the assembly of decapping complexes and RNP granules.
Jonas et al. (2013)
2 more