› 2vxf

Solution NMR

Solution structure of the LSm-domain of zebrafish RAP55

Released:
DOI: 10.2210/pdb2vxf/pdb
PDB entry 2vxf coloured by chain, ensemble of 20 models, front view.
PDB entry 2vxf coloured by chain, ensemble of 20 models, side view.
PDB entry 2vxf coloured by chain, ensemble of 20 models, top view.
Source organism: Danio rerio
Primary publication:
Similar modes of interaction enable Trailer Hitch and EDC3 to associate with DCP1 and Me31B in distinct protein complexes.
Tritschler F, Eulalio A, Helms S, Schmidt S, Coles M, Weichenrieder O, Izaurralde E, Truffault V
Mol Cell Biol 28 6695-708 (2008)
PMID: 18765641

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-181993 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sm domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 95 amino acids
Theoretical weight: 10.7 KDa
Source organism: Danio rerio
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q7SXR4 (Residues: 1-85; Coverage: 100%)
Gene names: lsm14a, lsm14aa
Sequence domains: Scd6-like Sm domain
Structure domains: SH3 type barrels.

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: XPLOR
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

14 review citations

Spinal muscular atrophy: why do low levels of survival motor neuron protein make motor neurons sick?
Burghes et al. (2009)
13 more

1 mention without citation

Similar modes of interaction enable Trailer Hitch and EDC3 to associate with DCP1 and Me31B in distinct protein complexes.
Tritschler et al. (2008)