› 2vz5

X-ray diffraction
1.74Å resolution

Structure of the PDZ domain of Tax1 (human T-cell leukemia virus type I) binding protein 3

Released:
DOI: 10.2210/pdb2vz5/pdb
PDB entry 2vz5 coloured by chain, front view.
PDB entry 2vz5 coloured by chain, side view.
PDB entry 2vz5 coloured by chain, top view.
Source organism: Homo sapiens
Entry authors: Murray JW, Shafqat N, Yue W, Pilka E, Johannsson C, Salah E, Cooper C, Elkins JM, Pike AC, Roos A, Filippakopoulos P, von Delft F, Wickstroem M, Bountra C, Edwards AM, Arrowsmith CH, Oppermann U

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-127187 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tax1-binding protein 3 Chain: A
Molecule details ›
Chain: A
Length: 139 amino acids
Theoretical weight: 15.66 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: O14907 (Residues: 11-124; Coverage: 92%)
Gene names: TAX1BP3, TIP1
Sequence domains: PDZ domain
Structure domains: Pdz3 Domain

Ligands and Environments

3 bound ligands:
Ligand IMD 2 x IMD
Ligand ZN 2 x ZN
Ligand CL 1 x CL
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X10SA
Spacegroup: P6522
Unit cell:
a: 59.813Å b: 59.813Å c: 121.289Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.176 0.174 0.226
Expression system: Escherichia coli

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