› 2w3c

X-ray diffraction
2.22Å resolution

Globular head region of the human general vesicular transport factor p115

Released:
DOI: 10.2210/pdb2w3c/pdb
PDB entry 2w3c coloured by chain, front view.
PDB entry 2w3c coloured by chain, side view.
PDB entry 2w3c coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Unusual armadillo fold in the human general vesicular transport factor p115.
Striegl H, Roske Y, Kümmel D, Heinemann U
PLoS One 4 e4656 (2009)
PMID: 19247479

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-130087 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
General vesicular transport factor p115 Chain: A
Molecule details ›
Chain: A
Length: 577 amino acids
Theoretical weight: 64.34 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: O60763 (Residues: 53-629; Coverage: 60%)
Gene names: USO1, VDP
Sequence domains:
Structure domains: Leucine-rich Repeat Variant

Ligands and Environments

1 bound ligand:
Ligand PEG 3 x PEG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: BESSY BEAMLINE 14.2
Spacegroup: C2
Unit cell:
a: 175.55Å b: 68.89Å c: 85.75Å
α: 90° β: 108.74° γ: 90°
R-values:
R R work R free
0.222 0.219 0.269
Expression system: Escherichia coli BL21(DE3)

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Citations

4 review citations

Role of vesicle tethering factors in the ER-Golgi membrane traffic.
Sztul et al. (2009)
3 more

7 mentions without citation

Structure of Golgi transport proteins.
Kümmel et al. (2011)
6 more